Apomorphine has a therapeutic effect on neglect produced by unilateral dorsomedial prefrontal cortex lesions in rats
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Ipsilesional spatial bias after a focal cerebral infarction in the medial agranular cortex: A mouse model of unilateral spatial neglect
2021, Behavioural Brain ResearchCitation Excerpt :Previous studies evaluating the orienting movements in rats have used a variety of tasks. For example, rats held by the experimenter's hands were evaluated based on the degree of the head orientation to the visual, auditory, and tactile stimuli presented from the left and right spaces [12,17,34–38]. Recent studies evaluated the orienting movements of rats using the spatial visual attention task [39] and the clicks accumulation task [18,40].
Prefrontal neural dynamics in consciousness
2019, NeuropsychologiaCitation Excerpt :This cognitive availability can be attained by preserving the content of consciousness in working memory (Horst and Laubach, 2009; Hupalo and Berridge, 2016; Klaassen et al., 2014; Mottaghy et al., 2002) as a single perceptive unit (Vargo et al., 1988). Decades ago, Vargo and other researchers indicated that when you selectively injure left and right dorsomedial cortices in rats, it produces severe polymodal neglect (Corwin et al., 1986; Cowey and Bozek, 1974; Vargo et al., 1989, 1988). Similar results have been reported in more recent research (Christakou et al., 2005; Lucchetti et al., 1998).
Noradrenergic antagonists mitigate amphetamine-induced recovery
2017, Behavioural Brain ResearchCitation Excerpt :An incision was made in the dura mater extending the length of the skull window to expose the underlying medial agranular cortex (AGm). Then, the AGm was removed by gentle aspiration down to the white matter with the use of a fine-gauge pipette attached to a suction pump [14,42,43]. Following hemostasis, gelfoam was gently placed into the lesion cavity.
Pharmacological Treatment of Visuospatial Neglect: A Systematic Review
2017, Journal of Stroke and Cerebrovascular DiseasesThe time-dependent and persistent effects of amphetamine treatment upon recovery from hemispatial neglect in rats
2015, Behavioural Brain ResearchCitation Excerpt :Subjects were tested for the presence of neglect 4–6 h after neglect surgery and then twice a week for 8 weeks during the light phase of the light/dark cycle with the experimenter blind to the subjects’ conditions. Neglect testing was a modification of the testing procedure developed by Crowne and Pathria [12] and is described in detail in previous publications [11,40,44]. Following observation of circling behavior, subjects were taken out of their cage and placed directly on the testing platform.
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Dr. Hashimoto's present address is Department of Neuropsychiatry, Kinki University School of Medicine, Osaka 589, Japan.