The role of dopamine and AMPA/kainate receptors in the nucleus accumbens in the hypermotility response to MK801
References (38)
- et al.
“Selective” D-1 and D-2 receptor antagonists fail to differentially alter supersensitive locomotor behavior in the rat
Life Sci.
(1986) - et al.
Amnesic effect of the novel anticonvulsant, MK801
Pharmacol. Biochem. Behav.
(1988) - et al.
The role of endogenous dopamine in the hypermotility response to intra-accumbens AMPA
Brain Res.
(1991) - et al.
Interactions between glutamatergic and monoaminergic systems within the basal ganglia-Implications for schizophrenia and Parkinson's disease
Trends Neurosci.
(1990) - et al.
Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems
Pharmacol. Biochem. Behav.
(1990) - et al.
Noncompetitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons
Neurosci. Lett.
(1990) - et al.
The modulation of dopaminergic transmission in the striatum by MK-801 is independent of presynaptic mechanisms
Neuropharmacology
(1992) - et al.
Stimulatory effect of N-methyl aspartate on locomotor activity and transmitter release from rat nucleus accumbens
Pharmacol. Biochem. Behav.
(1986) - et al.
The reserpine-sensitive dopamine pool mediates (+)-amphetamine-conditioned reward in the place preference paradigm
Brain Res.
(1990) - et al.
Selective 6-OHDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant induced locomotor activity in rats
Eur. J. Pharmacol.
(1976)
The N-methyl-D-aspartate receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats
Neuroscience. Lett.
The behavioural effects of MK-801 in rats: Involvement of dopaminergic, serotonergic and noradrenergic systems
Eur. J. Pharmacol.
From motivation to action: Functional interface between the limbic system and the motor system
Prog. Neurobiol.
In vivo demonstration of the enhancement of MK801 by L-glutamate
Life Sci.
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens
Pharmacol. Biochem. Behav.
The behavioural effects of MK801: A comparison with antagonists acting noncompetitively and competitively at the NMDA receptor
Eur. J. Pharmacol.
Glutamate-dopamine functional interaction within the striatum and the nucleus accumbens
Soc. Neurosci. Abstr.
Ethanol behaves as an NMDA antagonist with respect to locomotor stimulation in monoamine-depleted mice
J. Neural Transm.
The NMDA antagonist MK801 causes marked locomotor stimulation in monoamine-depleted mice
J. Neural Transm.
Cited by (78)
Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: Focus on nicotine effects
2015, Progress in NeurobiologyCitation Excerpt :GluRs are certainly involved in the transition from tonic to burst firing of DA neurons, but the published data are conflicting. Intra-VTA injection of an NMDAR antagonist (MK801) induces locomotor sensitisation (Willins et al., 1993) and increases the firing of DA neurons (French and Ceci, 1990; French et al., 1993), but similar behaviours have also been observed following the intra-VTA administration of NMDAR agonists (Suaud-Chagny et al., 1992; Seutin et al., 1994; Westerink et al., 1996; Webb et al., 2012). A recent study by Ducrot et al. (2013) has clarified some inconsistencies concerning the role of the NMDARs in the VTA by showing that blocking GluN2A* NMDAR in the VTA increases the reinforcing effects induced by ICSA, whereas blocking AMPAR induces the opposite effect.
Differential effects of 7-OH-DPAT and apomorphine on hyperactivity induced by MK-801 (dizocilpine) in rats
2005, NeuropharmacologyCitation Excerpt :Histological locations of cannula placements are shown in Fig. 3. MK-801 dose-dependently induced hyperactivity, in accord with several prior reports (e.g., Ford et al., 1989; Carlsson and Carlsson, 1989; Maj et al., 1991; Löscher and Honack, 1992; Willins et al., 1993). This effect may be due to activation of the mesocorticolimbic DA system, as MK-801 increases DA turnover in the NAS (Bristow et al., 1993).