Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

doi:10.1016/0092-8674(92)90430-K

Cell

Volume 70, Issue 4, 21 August 1992, Pages 609-620

https://doi.org/10.1016/0092-8674(92)90430-K Get rights and content

Abstract

Loss-of-function mutations in the yan gene result in the differentiation of supernumerary photoreceptors in the Drosophila eye. The yan gene encodes a protein with an ETS DNA-binding domain that accumulates in the nuclei of undifferentiated cells during the early stages of eye development. Our data suggest that yan functions as a cell-autonomous negative regulator of photoreceptor development; in the presumptive R7 and cone cells, yan appears to act antagonistically to the proneural signal mediated by sevenless and Ras1.

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Cell

ArticleNegative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

Abstract

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Article
Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein