Effect of CCK-8 on audiogenic epileptic seizure in P77PMC rats
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A prospective study on changes in blood levels of cholecystokinin-8 and leptin in patients with refractory epilepsy treated with the ketogenic diet
2016, Epilepsy ResearchCitation Excerpt :The anticonvulsive action of CCK has also been proven in various animal studies. Intracerebroventricular administration of CCK-8 in rats and intraperitoneal administration in mice and rats diminished seizures induced by different provoking mechanisms in epilepsy models (Kadar et al., 1987, 1984, 1983; Zhang et al., 1993). CCK-8 also amplified the anti-convulsive effect of the AED vigabatrine in a rat model for human partial epilepsy (Ferraro and Sardo, 2009).
Changes in cholecystokinin mRNA expression after amygdala kindled seizures: An in situ hybridization study
1996, Molecular Brain Research
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