Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms
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Frontal lobes dysfunction across clinical clusters of acute schizophrenia
2022, Revista de Psiquiatria y Salud MentalCitation Excerpt :All subjects were receiving antipsychotics. We computed the five dominant components of variation in our sample using PCA and largely replicated the PCA of previous studies.9,10,12,43 The present PCA decomposition of PANSS items accounted for 57% of the variance across symptom scales.
Clinical utility of the Negative Symptom Assessment-16 in individuals with schizophrenia
2019, European NeuropsychopharmacologyCitation Excerpt :This factor is similar to the emotion and retardation factor of the NSA-16 identified by Popp et al. (2012). Expressive gestures are a part of the affective blunting/diminished expression domain of negative symptoms (Ahmed et al., 2018; Garcia-Portilla et al., 2015; Keefe et al., 1992; Kring et al., 2013), although in the original work with the NSA-16, this symptom loaded on a motor retardation factor. Prolonged time to respond and slowed and reduced movements (motor retardation) are components of psychomotor slowing in schizophrenia (Morrens et al., 2007).
Identifying a system of predominant negative symptoms: Network analysis of three randomized clinical trials
2016, Schizophrenia Research
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Richard S.E. Keefe, Ph.D., Seth H. Apter, Ph.D., and James Schmeidler, Ph.D., are Assistant Professor; Philip D. Harvey, Ph.D., Department of Psychiatry, Mount Sinai School of Medicine, New York, NY.
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Philip D. Harvey, Ph.D., and Michael Davidson, M.D., are Associate Professors; Department of Psychiatry, Mount Sinai School of Medicine, New York, NY.
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Mark F. Lenzenweger, Ph.D., is Assistant Professor, Psychopathology Area, Department of Human Development, Cornell University, Ithaca, NY.
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Richard C. Mohs Ph.D., is Professor, and Department of Psychiatry, Mount Sinai School of Medicine, New York, NY.
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Kenneth L. Davis, M.D., is Professor and Chairman, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY.