Elsevier

Neuroscience Research

Volume 11, Issue 2, July 1991, Pages 141-145
Neuroscience Research

Short communication
Ultrastructural localization of telencephalin, a telencephalon-specific membrane glycoprotein, in rabbit olfactory bulb

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Abstract

Localization of a telencephalon-specific glycoprotein, telencephalin (TCLN), in the olfactory bulb of the rabbit was studied with an electron microscope. Anti-TCLN antisera appeared to stain plasma membrane, Golgi apparatus and multivesicular bodies of granule cells which are local circuit interneurons in the bulb. Principal neurons, mitral and tufted cells, were not immunoreactive. No glial cells showed immunoreactivity. Thus, expression of telencephalin is specific not only to the telencephalic segment of the brain, but also to the neuronal types.

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Present address: Department of Biochemistry, Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan.

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