Elsevier

Peptides

Volume 9, Issue 1, January–February 1988, Pages 165-171
Peptides

Substance P- and CGRP-immunoreactive nerves in bone

https://doi.org/10.1016/0196-9781(88)90023-XGet rights and content

Abstract

The present study demonstrates the occurrence of substance P (SP)- and calcitonin gene related peptide (CGRP)-immunoreactive nerve fibres in bone, bone marrow, periosteum, synovial membrane and soft tissues adjacent to the bone. The distribution pattern of the two types of nerves was similar, although the CGRP-positive fibres generally were more numerous. Both types of nerves were particularly abundant near the epiphyseal plate, in the bone marrow of patella and epiphyses, and in the periosteum. Many SP- and CGRP-immunoreactive fibres were also observed around blood vessels.

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  • Cited by (0)

    These results have in part been reported at the 33rd Annual Meeting, Orthopaedic Research Society, San Francisco, January, 1987 [2].

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