Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia
References (7)
- et al.
Distribution of glutamate decarboxylase, choline acetyltransferase and aromatic amino acid decarboxylase in the basal ganglia of normal and operated rats
Evidence for striatopallidal, striatoentopeduncular and striatonigral GABAergic fibres
Brain Res.
(1978) - et al.
Origin and distribution of glutamate decarboxylase in the nucleus subthalamicus of the cat
Brain Res.
(1978) - et al.
Experimental hemiballism in the monkey produced by unilateral kainic acid lesion in corpus Luysii
Brain Res.
(1979)
Cited by (42)
Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease
2012, Progress in NeurobiologyCitation Excerpt :Experimental studies in naïve monkeys have shown that electrolytic (Whittier and Mettler, 1949; Carpenter et al., 1950) or excitotoxic lesions (Hammond et al., 1979; Hamada and DeLong, 1992) restricted to the STN result in dyskinesias that are similar to those in humans with hemiballism. Also the application of GABAA receptor antagonists, such as picrotoxin (Crossman et al., 1980) or bicuculline (Crossman et al., 1984; Karachi et al., 2009), to the monkey STN can induce dyskinetic movements of the contralateral limbs that, when severe, resemble hemiballism. A similar injection in the monkey zona incerta (just above the STN) induces torticollis and rotational behavior, alone or in addition to contralateral limb dyskinesia (Crossman et al., 1984).
Debate: Do chorea and ballism make up a continuum?
2007, Revue NeurologiqueDeep brain stimulation for movement disorders
1998, Neurosurgery Clinics of North AmericaThe effects of reversible inactivation of the subthalamopallidal pathway on the behaviour of naive and hemiparkinsonian monkeys
1997, Journal of Clinical NeuroscienceBehavioral and neurochemical consequences of ibotenic acid lesion in the subthalamic nucleus of the common marmoset
1995, Brain Research Bulletin