Elsevier

Neuroscience Letters

Volume 20, Issue 3, December 1980, Pages 369-372
Neuroscience Letters

Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia

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Abstract

Hemiballismus was produced experimentally in the baboon by injection of the gamma-aminobutyric acid (GABA) antagonist picrotoxin into the globus pallidus/subthalamic nucleus of the conscious animal. The abnormal movements appeared in the limbs contralateral to the injected side and were of a character similar to those reported following lesions of the subthalamic nucleus.

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