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2020, Journal of Thoracic and Cardiovascular SurgeryPerioperative analgesia outcomes and strategies
2014, Best Practice and Research: Clinical AnaesthesiologyPre-emptive or preventive analgesia - lessons from the human literature?
2014, Veterinary Anaesthesia and AnalgesiaEarly visceral pain predicts chronic pain after laparoscopic cholecystectomy
2014, PainCitation Excerpt :Viewing the results as a whole, there are several possible explanations for the association between the early visceral pain response and the development of chronic pain, which are not necessarily mutually exclusive. One is that patients may suffer from preoperative central sensitization [8–10,29,34–36], possibly caused by more frequent biliary pain attacks, resulting in increased visceral postoperative pain and turning into a chronic visceral pain condition. As previously discussed, our tests may not be sufficient to find such sensitization.
Pre-emptive analgesia by nerve stimulator guided pudendal nerve block for posterior colpoperineorrhaphy
2012, European Journal of Obstetrics and Gynecology and Reproductive BiologyCitation Excerpt :The concept of pre-emptive analgesia to reduce postoperative pain was founded on a series of successful animal experimental studies that demonstrated central nervous system plasticity and sensitization after nociception [1].
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2012, PainCitation Excerpt :The molecular and physiological changes that underpin central sensitization may occur within hours after peripheral inflammation or nerve injury on the ipsilateral side and within 24 h on the contralateral side of the spinal cord [39,53]. Because central sensitization has been shown to influence spinally mediated motor programs such as nociceptive withdrawal reflexes and simple motor learning tasks, it is conceivable that it also affects voluntary motor control [8,9,34,52]. Additionally, an increasing number of studies have found prominent supraspinal changes in CRPS.