Neurotensin in the human brain
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Cited by (128)
Are periaqueductal gray and dorsal raphe the foundation of appetitive and aversive control? A comprehensive review
2019, Progress in NeurobiologyCitation Excerpt :The peptide neurotensin, which has a proposed modulatory influence over dopaminergic systems, is present in the human and monkey PAG as one of the most concentrated regions for neurotensin in the midbrain and brain stem (Cooper et al., 1981; Kataoka et al., 1979). Neurotensin fibers are evenly distributed over all subdivisions of the mammalian PAG/DR (Jennes et al., 1982; Mai et al., 1987), while cells are present mostly within the VLPAG and DR, and are known to project to the magnus raphe (Beitz et al., 1983b). Centrally administered neurotensin provokes a series of autonomic changes in the rat, including sedation and reduced locomotion.
An autoradiographic study of neurotensin receptors in the human hypothalamus
2014, Acta HistochemicaCitation Excerpt :The present anatomical data are consistent with the view that NT present in the preoptic area could mediate the stimulatory effects of estrogen on LHRH secretion (Alexander and Leeman, 1992). The preoptic region, which is also implicated in the control of other functions as thermoregulation (Briese, 1998), contains high amounts of endogenous peptide (Mai et al., 1987) and NT binding sites as shown in the present study, suggesting its involvement in the control of central temperature. This is supported by pharmacological studies showing that intracerebral injection of NT or its analogs, significantly influence central temperature, by causing hypothermia (Gordon et al., 2003).
Periaqueductal Gray
2012, The Human Nervous System, Third EditionAmygdala
2012, The Human Nervous System, Third EditionHypothalamus
2012, The Human Nervous System, Third EditionWhere and what is the paralaminar nucleus? A review on a unique and frequently overlooked area of the primate amygdala
2012, Neuroscience and Biobehavioral ReviewsCitation Excerpt :Interestingly, this distribution is similar to the pattern of TH-positive fibers in the PL (reviewed above), suggesting possible co-localization. NT cell bodies in this region are negligible (Mai et al., 1987; Zech et al., 1986) SST is found in developing neurons (Le Verche et al., 2009; Yacubova and Komuro, 2002) and is also a potent neuromodulator (Epelbaum et al., 1994).