Characterization of the mouse gene encoding the neuronal intermediate filament protein α-internexin
References (7)
- et al.
Structure of the gene for the neuronal intermediate filament protein α-internexin and functional analysis of its promoter
J. Biol. Chem.
(1991) Identification of previously unrecognized sequence motifs at the extreme carboxyterminus of the neurofilament subunit NF-M
Biochem. Biophys. Res. Commun.
(1989)- et al.
The predicted amino acid sequence of α-internexin is that of a novel neuronal intermediate filament protein
EMBO J.
(1990)
Cited by (17)
Proteomic analysis of the hippocampus in Alzheimer's disease model mice by using two-dimensional fluorescence difference in gel electrophoresis
2013, Neuroscience LettersCitation Excerpt :Thus, Aβ oligomers might lead to increasing the amounts of actin and tubulin. Spot nos. 5 and 2 were identified as α-internexin and NFL, respectively, which are known as neuronal intermediate proteins [2,18]. The amounts of α-internexin and NFL were significantly decreased.
Defined culture medium for stem cell differentiation: Applicability of serum-free conditions in the mouse embryonic stem cell test
2011, Toxicology in VitroCitation Excerpt :The brain specific type IV intermediate filament protein α-internexin is mainly expressed by immature neurons preceding the expression of neuronal intermediate filament proteins (Kaplan et al., 1990), and is widely expressed during development and through adulthood. It is a major component of the intermediate filament network in small interneurons and cerebellar granule cells (Chien and Liem, 1994; Pachter and Liem, 1985). The neuron-specific cytoskeletal protein βΙΙΙ-tubulin is expressed at the earliest phase of neuronal differentiation and strongest during periods of axon guidance and maturation (Liu et al., 2007; Tischfield et al., 2010).
Chapter 12 Cytoskeletal Abnormalities in Amyotrophic Lateral Sclerosis/Motor Neuron Disease
2003, Blue Books of Practical NeurologyNo requirement of α-internexin for nervous system development and for radial growth of axons
1999, Molecular Brain Research