Review articleRole of human fetal ependyma☆
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Bilateral open lip schizencephaly
2022, Annals of Medicine and SurgeryCitation Excerpt :Our case was bilateral open lip type of schizencephaly. The cause is unknown but failure of neuronal migration along the radially oriented glial cells in the brain cortex due to any type of insult and resultant hypoxemia with infarction in the 8th week of gestation is hypnotized [9,10]. Additionally viral infection (cytomegalovirus) and more recently Zika virus, attempted abortion, hypoxia, maternal age and trauma are also involved [6,11,16].
Timing in Neural Maturation: Arrest, Delay, Precociousness, and Temporal Determination of Malformations
2015, Pediatric NeurologyCitation Excerpt :An epigenetic overexpression compensates for synaptic loss from degenerating, dying neurons. The ependyma of the fetal brain has long basal processes that serve many functions not needed in the mature brain.93 The differentiation of the ependyma at the ventricular surface follows a precise spatial and temporal sequence that terminates with the complete lining of the lateral ventricles at 22 weeks' gestation.
Ependyma, Choroid
2013, Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing CNS and PNSNeuroembryology and brain malformations: An overview
2013, Handbook of Clinical NeurologyCitation Excerpt :All cells forming this pseudostratified columnar epithelium are attached by a narrow cytoplasmic strand to the ventricular wall at the proximal end and the pial surface of the neural tube or brain at the distal end, through which the nucleus travels to-and-fro in its different phases of the mitotic cycle, forming mitotic spindles to divide mainly at the ventricular wall. Differentiation of an ependyma at the ventricular surface arrests further mitoses at that site and all cells become premigratory and nonproliferative (Sarnat, 1992c). Ependyma does not cover the entire lateral ventricular surfaces until 22 weeks’ gestation (Sarnat, 1992b).
History of research concerning the ependyma: a view from inside the human brain
2023, Frontiers in Cellular Neuroscience
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This work is supported by a grant from the Alberta Children's Hospital Foundation.