Neuron
ArticleA diffusible second messenger mediates one of the pathways coupling receptors to calcium channels in rat sympathetic neurons
References (39)
- et al.
Inhibition of Ca2+ and K+ channels in sympathetic neurons by neuropeptides and other ganglionic transmitters
Neuron
(1990) - et al.
Measurement of Ca2+ concentrations in living cells
Prog. Biophys. Mol. Biol.
(1982) M-currents: an update
Trends Neurosci.
(1988)- et al.
LHRH and GTPy-S modify calcium current activation in bullfrog sympathetic neurons
Neuron
(1990) - et al.
Control of calcium current in sat sympathetic neurons by norepinephrine
Brain Res.
(1982) - et al.
Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons
Neuron
(1989) - et al.
Specific inhibitors of protein kinase C block transmitter-induced modulation of sensory neuron calcium current
Neuron
(1989) - et al.
Ca2+ channels in rat central and peripheral neurons: high-threshold current resistant to dihydropyridine blockers and ω-conotoxin
Neuron
(1991) - et al.
Neuropeptide Y blocks a calcium current in C cells of bullfrog sympathetic ganglia
Eur. J. Pharmacol.
(1988) - et al.
Different GTP-binding proteins mediate regulation of calcium channels by acetylcholine and noradrenaline in rat sympathetic neurons
Brain Res.
(1989)
Staurosporine, a potent inhibitor of phospholipid/Ca++ dependent protein kinase
Biochem. Biophys. Res. Commun.
Multiple types of neuronal calcium channels and their selective modulation
Trends Neurosci.
The electrical response of turtle cones to flashes and steps of light
J. Physiol.
Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons
Accumulation of inositol phosphates in sympathetic ganglia
Biochem. J.
Modulation of M current in frog sympathetic ganglion cells
Rapid kinetics of second messenger formation in olfactory transduction
Nature
Cyclic nucleotide metabolism in the sympathetic ganglion
Cell. Mol. Neurobiol.
Muscarinic receptors in rat sympathetic ganglia
J. Pharmacol.
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Regulation of neural ion channels by muscarinic receptors
2018, NeuropharmacologyGABA<inf>B</inf> receptors inhibit low-voltage activated and high-voltage activated Ca<sup>2+</sup> channels in sensory neurons via distinct mechanisms
2015, Biochemical and Biophysical Research CommunicationsCitation Excerpt :Here we investigated additional ways by which peripheral GABAB receptors might influence nociceptive transmission. GABAB, similar to other Gi/o-coupled receptors, inhibit HVA currents using a ‘fast’ pathway that involves direct interaction of G protein with the channels [34–38] resulting in a conformational change of the channel complex that makes it harder to open by voltage [39,40]. There are also number of other pathways by which GPCR can inhibit VGCC, including phosphatidylinositol 4,5-bisphosphate (PIP2) depletion [41,42], arachidonic acid [43] and Src kinase [15].
Phosphoinositides regulate ion channels
2015, Biochimica et Biophysica Acta - Molecular and Cell Biology of LipidsRegulation of Ca<inf>V</inf>2 calcium channels by G protein coupled receptors
2013, Biochimica et Biophysica Acta - BiomembranesPIP<inf>2</inf> hydrolysis is responsible for voltage independent inhibition of Ca<inf>V</inf>2.2 channels in sympathetic neurons
2013, Biochemical and Biophysical Research CommunicationsCitation Excerpt :Muscarinic agonists reduce calcium current by two different components: one, fast and PTX-sensitive and the other slow, PTX-insensitive and calcium-dependent. The latter seems not to shift voltage dependence of the channels [5,10]. The current modulated under this muscarinic component has similar characteristics of the current regulated by the voltage independent pathway [6].
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Present address: Department of Pharmacology, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, England.