Neuron
ArticleThe contribution of NMDA and Non-NMDA receptors to the light-evoked input-output characteristics of retinal ganglion cells
References (57)
- et al.
Kynurenic acid distinguishes kainate and quisqualate receptors in the vertebrate retina
Brain Res.
(1986) - et al.
Differential effects of excitatory amino acids on dorsal horn nociceptive neurons in the rat
Brain Res.
(1990) - et al.
Transmitter circuits in the vertebrate retina
Prog. Neurobiol.
(1987) - et al.
The physiology of excitatory amino acids in the vertebrate central nervous system
Prog. Neurobiol.
(1987) The recording of action potential currents as an assessment fordrug actions on excitablecells
J. Pharmacol. Meth.
(1991)- et al.
Whole-cell patch-clamp recordings of an NMDA receptormediated synaptic current in rat hippocampal slices
Neurosci. Lett.
(1990) - et al.
The contribution of NMDA and non-NMDA receptors to fast and slow transmission of sensory information in the rat S1 barrel cortex
J. Neurosci.
(1993) - et al.
Synaptic drive and impulse generation in ganglion cells of turtle retina
J. Physiol.
(1979) - et al.
NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus
Nature
(1989) - et al.
Computational implications of NMDA receptor channels
Strychnine blocks transient but not sustained inhibition in mudpuppy retinal ganglion cells
J. Physiol.
Actions of excitatory amino acids on brisk ganglion cells in the cat retina
J. Neurophysiol.
Do N-methyl-d-aspartate receptors mediate synaptic responses in the mudpuppy retina?
J. Neurosci.
Kainate receptormediated synaptic currents in mudpuppy inner retinal neurons reduced by D-O-phosphoserine
J. Neurophysiol.
Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons
Nature
Dual-component synaptic potentials in the lamprey mediated by excitatory amino acid receptors
J. Neurosci.
Dual-component amino-acidmediated synaptic potentials: excitatory drive for swimming in Xenopus embryos
J. Physiol.
2-Amino-5-phosphonovale rate (2APV), a highly potent and specific antagonist at spinal NMDA receptors
Br. J. Pharmacol.
Two types of glutamate receptors differentially excite amacrine cells in the tiger salamander retina
J. Physiol.
An intracellular analysis of the visual responses of neurones in cat visual cortex
J. Physiol.
A computer based model for realistic simulations of neural networks
Biol. Cybernet.
Intracellular recordings from single rods and cones in the mud puppy retina
Science
Modeling the repetitive firing of retinal ganglion cells
Brain Res.
Slow excitatory postsynaptic currents mediated by N-methyl-d-aspartate receptors on cultured mouse central neurons
J. Physiol.
The effect of varying stimulus intensity on NMDA-receptor activity in cat visual cortex
J. Neurophysiol.
Physiological and pharmacological basis of GABA and glycine action on neurons of mudpuppy retina. III. Amacrinemediated inhibitory influences on ganglion cell receptive-field organization: a model
J. Neurophysiol.
Cellular network underlying locomotion as revealed in a lower vertebrate model: transmitters, membrane properties, circuitry, and simulation
Analysis of excitatory synaptic action in pyramidal cells using whole-cell recording from rat hippocampal slices
J. Physiol.
Cited by (94)
Homeostatic plasticity in the retina
2023, Progress in Retinal and Eye Research1.11 - Decomposing a Cone's Output (Parallel Processing)
2020, The Senses: A Comprehensive Reference: Volume 1-7, Second EditionA Central Role for Mixed Acetylcholine/GABA Transmission in Direction Coding in the Retina
2016, NeuronCitation Excerpt :Most strikingly, AMPAR-mediated synaptic activity in DSGCs is absent at low contrast and only emerges at the higher-contrast levels. This is unusual, as in most ganglion cells the AMPAR conductance is the dominant excitatory conductance (Diamond and Copenhagen, 1993; Sagdullaev et al., 2006; Sethuramanujam and Slaughter, 2015; Zhang and Diamond, 2009), and AMPARs and NMDARs are usually activated in parallel when contrast (Buldyrev et al., 2012; Diamond and Copenhagen, 1995; Manookin et al., 2010) or temporal frequency (Stafford et al., 2014) is varied. Whether different types of bipolar cells differentially use NMDARs and AMPARs, or whether these receptors are expressed at the same synapses and the system relies on the distinct affinities of these receptors (Patneau and Mayer, 1990) to signal different levels of glutamate release evoked by varying contrasts remains to be investigated.
NMDA Receptors Multiplicatively Scale Visual Signals and Enhance Directional Motion Discrimination in Retinal Ganglion Cells
2016, NeuronCitation Excerpt :As shunting inhibition reduces the PSP amplitude, it simultaneously increases the driving force on the excitatory conductance such that the fractional reduction of larger PSPs by the shunt is decreased, leading to lower DSI (Figure S8Biv). These effects of decreased driving force can be offset by the voltage-dependent NMDAR conductance, which increases with depolarization over the physiological membrane potential range, causing the total excitatory synaptic drive to behave more like an ideal current source (Diamond and Copenhagen, 1993; Figures S8Ci and S8Cii) and enabling DSI to remain consistent over a larger response range (Figures S8Ciii and S8Civ). When DS is mediated by directionally tuned, Ohmic excitatory input (Figures S8Di and S8Dii), the PD excitatory conductance decreases the input resistance of the cell, making it harder for other excitatory conductances to depolarize the cell during a PD response.
Light-induced plasticity of synaptic ampa receptor composition in retinal ganglion cells
2012, NeuronCitation Excerpt :Changes in AMPAR subtype are generated via alterations in neuronal activity that accompany development, sensory deprivation, emotional stress, addiction, pain, disease, and high-frequency synaptic stimulation (Bellone and Lüscher, 2005; Clem and Barth, 2006; Grooms et al., 2000; Liu et al., 2010; Nagy et al., 2004; Opitz et al., 2000; Osswald et al., 2007; Vikman et al., 2008; Xia et al., 2007). Excitatory synapses on all functional classes (ON, OFF, and ON-OFF) of retinal ganglion cells (RGCs) utilize both GluA2-lacking, Ca2+-permeable AMPARs (CP-AMPARs) and GluA2-containing, Ca2+-impermeable AMPARs (CI-AMPARs) and NMDARs (Chen and Diamond, 2002; Diamond and Copenhagen, 1993; Lukasiewicz et al., 1997; Xia et al., 2007). As the retina encounters a dynamically changing visual scene, these synapses experience a wide range of neural activity.