Neuron
ArticleDifferential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neurons
References (45)
Calcium-mediated neurotoxicity-relationship to specific channel types and role in ischemic damage
Trends Neurosci.
(1988)- et al.
Long-term potentiation of guinea-pig mossy fiber responses is not blocked by N-methyl-d-aspartate antagonists
Neurosci. Lett.
(1986) - et al.
Isolation of neurons suitable for patch clamping form adult mammalian central nervous system
J. Neurosci. Meth.
(1986) - et al.
A selective binding site for 3H-NECA that is not an adenosine A2 receptor
Biochem. Pharmacol.
(1989) Activity-dependent release of ATP and adenosine derivatives can trigger molecular cascades for the memory process in the human brain
Jpn. J. Pharmacol.
(1990)- et al.
Excitatory and inhibitory effects of adenosine on the neurotransmission in the hippocampal slices of guinea-pig
Brain Res.
(1990) - et al.
Excitatory effect of adenosine on neurotransmission in the slices of superior colliculus and hippocampus of guinea pig
Neurosci. Lett.
(1990) - et al.
Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons
Neuron
(1989) - et al.
Adenosine inhibits calcium spikes in hippocampal pyramidal neurons in vitro
Neurosci. Lett.
(1983) - et al.
Ca2+ channels in rat central and peripheral neurons: high-threshold current resistant to dihydropyridine blockers and ω-conotoxin
Neuron
(1991)
Adenosine receptors and calcium: basis for proposing a third (A3) adenosine receptor
Prog. Neurobiol.
Analogs of caffeine with selectivity for A2 adenosine receptors
Life Sci.
Ca2+ evoked (H3)dopamine release from synaptosomes is dependent on neuronal type Ca2+ channels and is not mediated by acetylcholine, glutamate or aspartate release
J. Pharmacol. Exp. Ther.
Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes
Mol. Pharmacol.
Role of adenine nucleotides and inorganic phosphate in the regulation of skeletal muscle blood blow
Circ. Res.
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue
J. Physiol.
The physiological activity of adenine compounds with special reference to their action upon the mammalian heart
J. Physiol.
Interactions between the effects of adenosine and calcium on synaptic responses in rat hippocampus in vitro
J. Physiol.
Adenosine increases synaptic facilitation in the in vitro rat hippocampus: evidence for a presynaptic site of action
J. Physiol.
Modulation of neurotransmission by purine nucleosides and nucleotides
Biochem. Pharmacol.
Inhibition of noradrenaline release from hippocampal slices by a stable adenosine analogue
Acta Physiol. Scand.
Cited by (183)
Keep an eye on adenosine: Its role in retinal inflammation
2020, Pharmacology and TherapeuticsThe adenosine A<inf>2B</inf> G protein-coupled receptor: Recent advances and therapeutic implications
2019, Pharmacology and TherapeuticsCitation Excerpt :The A2BAR has been proposed to interact with Gq proteins to activate phospholipase C (PLC) leading to increased PKC activation and elevations of inositol triphosphate (IP3) and intracellular calcium (Linden, Thai, Figler, Jin, & Robeva, 1999). Ca2+ can also be mobilised via direct activation of calcium channels through a cholera toxin-sensitive mechanism likely downstream of Gβγ (Feoktistov, Murray, & Biaggioni, 1994) or indirectly via activation of PKA (Mogul, Adams, & Fox, 1993). The A2BAR also stimulates ERK1/2, c-Jun N-terminal Kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) signalling (Feoktistov, Goldstein, & Biaggioni, 1999; Gao, Chen, Weber, & Linden, 1999; Schulte & Fredholm, 2003), however there is ongoing debate as to which G protein is upstream of these intracellular second messengers (Aherne, Kewley, & Eltzschig, 2011).
Design and synthesis of novel xanthine derivatives as potent and selective A<inf>2B</inf> adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases
2017, European Journal of Medicinal ChemistryCitation Excerpt :A1 and A3AdoRs mediate inhibition of adenylate cyclase through Gi coupled pathway, whereas A2B and A2A stimulate adenylate cyclase activity via Gs coupling and result in increased intracellular cAMP levels [5]. In addition, coupling of A2A and A2BAdoRs to phospholipase C via Gq, resulting in mobilization of intracellular calcium and direct coupling to calcium channels (stimulation of calcium influx), have also been reported [7–9]. Adenosine has been shown to cause mast cell degranulation [10], vasodilation [11], chloride secretion in epithelial cells [12,13], growth inhibition of smooth muscle cells [14], and stimulation of glucose production in rat hepatocytes [15] and stimulate VEGF secretion [16] via activation of A2BAdoR.
IL-6, A1 and A2aR: A crosstalk that modulates BDNF and induces neuroprotection
2014, Biochemical and Biophysical Research CommunicationsIL-6 treatment increases the survival of retinal ganglion cells in vitro: The role of adenosine A1 receptor
2013, Biochemical and Biophysical Research CommunicationsPharmacology of signaling induced by dopamine D<inf>1</inf>-like receptor activation
2010, Pharmacology and Therapeutics
- †
Present address: Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208.