Invited reviewVisible light induced changes in the immune response through an eye-brain mechanism (photoneuroimmunology)
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Cited by (60)
Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS)
2021, MaturitasCitation Excerpt :Given there is no available literature on our studied association, it is not possible to compare our findings with those of others; however, our results are in line with a number of previous observations, which we elaborate below separately for estrogens and gonadotropins. It is likely that steroid hormones and gonadotropins are affected by different, yet tangled, mechanisms: Sex steroid concentrations are directly associated with vitamin D metabolites [9,45], which are derived from exposure to UVR radiation, while on the other hand, visible light, received by the retina, modulates the actions of the pineal and pituitary gland and thus could exhibit an effect on gonadotropins [46,47]. One possible mechanism explaining the statistically significant negative association between estrogens and UVR exposure is based on UVR derived vitamin D (cholecalciferol) being metabolized into calcidiol [48], and 17β-estradiol enhances the conversion of calcidiol to calcitriol, the active form of vitamin D, in the kidneys [45].
Effects of light intensity on growth, immune responses, antioxidant capability and disease resistance of juvenile blunt snout bream Megalobrama amblycephala
2015, Fish and Shellfish ImmunologyCitation Excerpt :Besides, chronic stress events may also affect the long-term physiology of fish, suppressing immune function [20]. Roberts (1995) [22] reported that visible light was received by the retina and was then transduced and delivered to the visual cortex, and also via an alternative pathway to the suprachiasmatic nucleus (SCN), which controlled circadian rhythm and neuroendocrine function. Visible light exposure can modulate the pituitary and pineal glands, which leads to the change of neuroendocrine function.
Effects of light intensity on growth, immune response, plasma cortisol and fatty acid composition of juvenile Epinephelus coioides reared in artificial seawater
2013, AquacultureCitation Excerpt :In return, these neuroendocrine changes can lead to immune modulation. Our study showed that the activities of immune-related enzymes were significantly increased at 320–1150 lx, which indicated that E. coioides had an optimum light intensity to stimulate retina and cause neuroendocrine changes through an eye–brain mechanism, resulting in increase in immune-related enzyme activities (Joan, 1995; Vihtelic and Hyde, 2000). In contrast, light intensity either too low or too high cannot be perceived well by retina, or retina may get damaged (Herve et al., 2007; Joan, 1995; Vihtelic and Hyde, 2000), so immune-related enzyme activities decrease, and there is no capacity to tolerate environmental stresses.
Photoimmunomodulation and melatonin
2010, Journal of Photochemistry and Photobiology B: Biology