Research reportEnhanced CREB phosphorylation and changes in c-Fos and FRA expression in striatum accompany amphetamine sensitization
References (45)
- et al.
Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals
Mol. Cell. Neurosci.
(1995) - et al.
Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat
Mol. Brain Res.
(1994) - et al.
Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum
Neuron
(1995) - et al.
Cocaine binges differentially alter striatal preprodynorphin and zif/268 mRNAs
Mol. Brain Res.
(1995) - et al.
Persistent reduction of immediate early gene mRNA in rat forebrain following single or multiple doses of cocaine
Mol. Brain Res.
(1994) - et al.
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
Cell
(1989) - et al.
Coadministration of a selective D1 or D2 dopamine agonist with methamphetamine prevents methamphetamine-induced behavioral sensitization and neurochemical change, studied by in vivo intracerebral dialysis
Brain Res.
(1991) - et al.
Induction of a long-lasting AP-1 complex composed of altered fos-like proteins in brain by chronic cocaine and other chronic treatments
Neuron
(1994) - et al.
Preexposure sensitizes rats to the rewarding effects of cocaine
Pharm. Biochem. Behav.
(1990) - et al.
Amphetamine regulation of mesolimbic dopamine-cholecystokinin neurotransmission
Brain Res.
(1992)
Cocaine reinforcement and extracellular dopamine overflow: an in vivo microdialysis study
Brain Res.
(1989)
Acute and chronic amphetamine treatments differentially regulate neuropeptide messenger RNA levels and Fos immunoreactivity in rat striatal neurons
Neuroscience
(1995)
DNQX blockade of amphetamine behavioral sensitization
Brain Res.
(1991)
Drugs of abuse: anatomy, pharmacology and function of reward pathways
Trends Pharmacol. Sci.
(1992)
Regulation of cAMP-inducible genes by CREB
Trends Neurosci.
(1990)
Drug addiction: a model for the molecular basis of neural plasticity
Neuron
(1993)
Competitive and noncompetitive NMDA antagonists block sensitization to methamphetamine
Pharmacol. Biochem. Behav.
(1994)
Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress
Mol. Brain Res.
(1993)
Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration
Brain Res.
(1990)
Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis
Brain Res. Rev.
(1986)
The neural basis of drug craving: an incentive-sensitization theory of addiction
Brain Res. Rev.
(1993)
Persistent sensitization of dopamine neurotransmission in ventral striatum (nucleus accumbens) produced by prior experience with (+)-amphetamine: a microdialysis study in freely moving rats
Brain Res.
(1988)
Cited by (116)
Neurobiological mechanisms underlying psychostimulant use
2023, Current Opinion in NeurobiologyTime-dependent changes in striatal monoamine levels and gene expression following single and repeated amphetamine administration in rats
2021, European Journal of PharmacologyCitation Excerpt :Furthermore, amphetamine downregulated the expression of CREB in the nucleus accumbens at 90 min. The CREB downregulation may appear discordant with the evidence that single or repeated exposures to psychostimulants induce CREB phosphorylation in the nucleus accumbens and the dorsal striatum without affecting total CREB levels (Konradi et al., 1994; Turgeon et al., 1997; Shi and McGinty, 2007). In fact, CREB activation has been posited to be necessary for acute cocaine administration to provoke expression changes in the striatum (Lemberger et al., 2008).
The Effects of Amphetamine and Methamphetamine on Brain Activity-Related Immediate Early Gene Expression
2016, Neuropathology of Drug Addictions and Substance MisuseThe Effects of Amphetamine and Methamphetamine on Brain Activity-Related Immediate Early Gene Expression
2016, Neuropathology of Drug Addictions and Substance Misuse Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects
- 1
Present address: Department of Psychology, Amherst College, Amherst, MA 01002, USA.
- 2
Present address: Department of Psychology, Brown University, Box 1853, Providence, RI 02912, USA.
Copyright © 1997 Published by Elsevier B.V.