Current Biology
Volume 10, Issue 4, 15 February 2000, Pages R137-R140
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Gene silencing: Shrinking the black box of RNAi

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Abstract

The mysterious mechanism whereby the mere presence of double-stranded RNA can inactivate specific genes is yielding its secrets. Recent results identifying cellular components required for RNAi in Caenorhabditis elegans indicate that the mechanism is conserved, ancient and may provide a defense against selfish DNA.

Keywords

Biochemistry
Genetics

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