Reflection and ReactionDefinition of refractory epilepsy: defining the indefinable?
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2021, Epilepsy and BehaviorCitation Excerpt :Epilepsies are neurological disorders characterized by the presence of epileptic seizures and neuropsychiatric comorbidities [1,2]. Despite the great variety of anticonvulsant drugs [3], the current pharmacological treatments cannot control seizures in one-third of the cases, and those patients are called pharmacoresistant [4,5]. Therefore, new therapeutical approaches are required to improve behavioral, neurological, and psychological alterations associated with epilepsies [2,6].
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