Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1812, Issue 3, March 2011, Pages 364-380
ReviewInvestigating regeneration and functional integration of CNS neurons: Lessons from zebrafish genetics and other fish species☆
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Research Highlights
► We review the robust innate regenerative potential of the zebrafish CNS. ► Radial glia have been identified as a major source of CNS stem cells. ► We examine the molecular pathways activated during regenerative processes. ► Innovative cell lesioning paradigms that induce regeneration are described. ► Emerging genetic and physiology tools recommend zebrafish for CNS regeneration studies.
Keywords
Zebrafish
Regeneration
Retina
Optic nerve
Spinal cord
Brain
Central nervous system
Stem cell
Glia
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This article is part of a Special Issue entitled Zebrafish Models of Neurological Diseases.
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