DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome
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Abbreviations
DS
Down syndrome
IP
intermediate progenitor
NSC
neural stem cell
RG
radial glia
SVZ
subventricular zone
VZ
ventricular zone
Keywords
Cell cycle regulation
DYRK kinases
Cerebral cortex development
Trisomy 21
Neurodevelopmental disorders
Intellectual disability
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Copyright © 2015 The Authors. Published by Elsevier B.V.