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Experimentally produced Cerebral Status Spongiosus and Continuous Pseudorhythmic Electroencephalographic Discharges with a Membrane-ATPase Inhibitor in the Rat

Abstract

IN an experimental investigation of sub-acute spongi-form encephalopathy1, which, according to some authors2,3, is a variety of Jakob-Creutzfeld disease, ouabain was intracranially injected into the rat.

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References

  1. Nevin, S., McMenemey, W. H., Behrman, S., and Jones, D. D., Brain, 83, 519 (1960).

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  2. Alem`, G., and Bignami, A., Riv. Sper. Freniat., 83 suppl., 1491 (1959).

  3. Siedler, H., and Malamud, N., J. Neuropath. Exp. Neurol., 22, 381 (1963).

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  4. Bonting, S. L., in Water and Electrolyte Metabolism (II), edit. by de Graeff, J., and Leijnse, B., 35 (1964).

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BIGNAMI, A., PALLADINI, G. Experimentally produced Cerebral Status Spongiosus and Continuous Pseudorhythmic Electroencephalographic Discharges with a Membrane-ATPase Inhibitor in the Rat. Nature 209, 413–414 (1966). https://doi.org/10.1038/209413a0

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