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A rapid, simple, and humane method for submandibular bleeding of mice using a lancet

Abstract

Methods for obtaining blood samples from mice tend to be difficult, inhumane, or both. The authors describe an inexpensive, disposable, single-use lancet for submandibular bleeding of mice that allows investigators to quickly draw 0.2–0.5 ml of blood without the use of anesthesia.

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Figure 1
Figure 2: (a) The Goldenrod animal bleeding lancet removed from the sterile wrapper.
Figure 3: (a) Positioning and poking the cheek with the lancet.
Figure 4
Figure 5

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Acknowledgements

Photos were provided by E. Clark.

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Correspondence to William T. Golde.

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Competing interests

All three authors are inventors of the patent-pending technology described here, and developed under a Cooperative Research and Development Agreement between the US Department of Agriculture, Agricultural Research Service and MEDIpoint, Inc.

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Golde, W., Gollobin, P. & Rodriguez, L. A rapid, simple, and humane method for submandibular bleeding of mice using a lancet. Lab Anim 34, 39–43 (2005). https://doi.org/10.1038/laban1005-39

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  • DOI: https://doi.org/10.1038/laban1005-39

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