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Myelin repair: developmental myelination redux?

A recent study of an Olig1 knockout mouse concludes that remyelination after injury may occur by a different mechanism from myelination during normal development, but another report suggests that this mouse model should be interpreted cautiously.

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Figure 1: Olig1 and oligodendrocyte differentiation.

References

  1. Arnett, H. et al. Science 306, 2111–2115 (2004).

    Article  CAS  Google Scholar 

  2. Xin, M. et al. J. Neurosci. 25, 1354–1365 (2005).

    Article  CAS  Google Scholar 

  3. Morell, P. et al. in Basic Neurochemistry 6th edn. (eds. Siegel, G., Agranoff, B., Albers, W., Fisher, S. & Uhler, M.) 69–94 (Lippincott-Raven, New York, 1999).

    Google Scholar 

  4. Salzer, J.L. Neuron 40, 297–318 (2003).

    Article  CAS  Google Scholar 

  5. Di Rocco, M. et al. Am. J. Med. Genet. 129B, 85–93 (2004).

    Article  Google Scholar 

  6. Liblau, R. et al. Trends Neurosci. 24, 134–135 (2001).

    Article  CAS  Google Scholar 

  7. Waxman, S. N. Engl. J. Med. 338, 323–325 (1998).

    CAS  PubMed  Google Scholar 

  8. Franklin, R. Nat. Rev. Neurosci. 3, 705–714 (2002).

    Article  CAS  Google Scholar 

  9. Lu, Q.R. et al. Neuron 25, 317–329 (2000).

    Article  CAS  Google Scholar 

  10. Zhou, Q. et al. Neuron 31, 791–807 (2001).

    Article  CAS  Google Scholar 

  11. Zhou, Q. & Anderson, D. Cell 109, 61–73 (2002).

    Article  CAS  Google Scholar 

  12. Lu, Q.R. et al. Cell 109, 75–86 (2002).

    Article  CAS  Google Scholar 

  13. Olson, E. et al. Cell 85, 1–4 (1996).

    Article  CAS  Google Scholar 

  14. Pham, C. et al. Proc. Natl. Acad. Sci. USA 93, 13090–13095 (1996).

    Article  CAS  Google Scholar 

  15. Doerflinger, N. et al. Genesis 35, 63–72 (2003).

    Article  CAS  Google Scholar 

Download references

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Balabanov, R., Popko, B. Myelin repair: developmental myelination redux?. Nat Neurosci 8, 262–264 (2005). https://doi.org/10.1038/nn0305-262

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