Abstract
Here we describe the expression pattern of GATA-2 in the developing chick hindbrain. We found that during the early period of neurogenesis this gene specifically labels a particular neuronal subtype, the contralateral vestibular-acoustic neurons of rhombomere 4, and that expression of this gene in these cells is transient. We also found that GATA-2 labels a broader territory of the ventral neural tube at later stages. As well as this hindbrain expression, we also describe expression of GATA-2 in the otic vesicle, oculomotor nucleus, third nerve and metanephros.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Chick Embryo
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DNA-Binding Proteins / genetics*
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DNA-Binding Proteins / metabolism
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Eye / embryology
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Eye / metabolism
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GATA2 Transcription Factor
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Gene Expression Regulation, Developmental*
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Homeodomain Proteins / immunology
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Homeodomain Proteins / metabolism
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LIM-Homeodomain Proteins
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Motor Neurons / metabolism
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Nerve Tissue Proteins*
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Rhombencephalon / embryology*
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Rhombencephalon / metabolism
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Transcription Factors / genetics*
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Transcription Factors / immunology
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Transcription Factors / metabolism
Substances
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DNA-Binding Proteins
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GATA2 Transcription Factor
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Homeodomain Proteins
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Isl-2 protein, vertebrate
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LIM-Homeodomain Proteins
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Nerve Tissue Proteins
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Transcription Factors
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insulin gene enhancer binding protein Isl-1