Abstract
The expression of eight murine Frizzled (1,3-9) genes was studied during mouse somitogenesis, in order to correlate the Wnt-dependent activation of myogenesis with the expression of specific Frizzled putative receptors. Frizzled 1, 3, 6, 7, 8, and 9 have specific expression in the forming and differentiating somites. The genes analyzed have a complex and partly overlapping pattern of expression in other regions of the embryo.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Brain / embryology
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Extremities / embryology*
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Frizzled Receptors
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Gene Expression Regulation, Developmental
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Mesoderm
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Mice
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Molecular Sequence Data
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Proto-Oncogene Proteins / metabolism*
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Receptors, Cell Surface / genetics*
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Receptors, Cell Surface / metabolism
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Receptors, G-Protein-Coupled*
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Receptors, Neurotransmitter / genetics*
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Receptors, Neurotransmitter / metabolism
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Wnt Proteins
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Xenopus Proteins*
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Zebrafish Proteins*
Substances
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FZD1 protein, Xenopus
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FZD1 protein, human
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FZD6 protein, human
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FZD8 protein, Xenopus
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Frizzled Receptors
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Fzd1 protein, mouse
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Fzd5 protein, mouse
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Fzd6 protein, mouse
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Fzd7 protein, mouse
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Fzd9 protein, mouse
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Proto-Oncogene Proteins
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Receptors, Cell Surface
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Receptors, G-Protein-Coupled
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Receptors, Neurotransmitter
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Wnt Proteins
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Xenopus Proteins
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Zebrafish Proteins
Associated data
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GENBANK/AF005203
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GENBANK/AF033585
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GENBANK/AF054623