Autoimmune T cells as potential neuroprotective therapy for spinal cord injury

Lancet. 2000 Jan 22;355(9200):286-7. doi: 10.1016/s0140-6736(99)05140-5.

Abstract

Autoimmune T cells against central nervous system myelin associated peptide reduce the spread of damage and promote recovery in injured rat spinal cord, findings that might lead to neuroprotective cell therapy without risk of autoimmune disease.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autoimmunity / immunology*
  • Central Nervous System / immunology
  • Magnetic Resonance Imaging
  • Myelin Basic Protein / immunology
  • Nerve Degeneration / prevention & control
  • Rats
  • Spinal Cord Injuries / immunology
  • Spinal Cord Injuries / therapy*
  • T-Lymphocytes / immunology*

Substances

  • Myelin Basic Protein