Abstract
Protein phosphatase 2A describes an extended family of intracellular protein serine/threonine phosphatases sharing a common catalytic subunit that regulates a variety of processes by means of diverse regulatory subunits. During the past year, studies have shown that protein phosphatase 2A influences events ranging from the initiation of DNA replication to vertebrate axis formation to apoptosis.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Apoptosis
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Calcium-Calmodulin-Dependent Protein Kinases / metabolism
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Cell Cycle
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Cytoskeletal Proteins / metabolism
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DNA Replication
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Glycogen Synthase Kinase 3
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Humans
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Phosphoprotein Phosphatases / chemistry
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Phosphoprotein Phosphatases / genetics
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Phosphoprotein Phosphatases / metabolism*
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Protein Phosphatase 2
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Protein-Tyrosine Kinases / metabolism
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Proto-Oncogene Proteins / metabolism
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Signal Transduction
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Trans-Activators*
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Wnt Proteins
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Zebrafish Proteins*
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beta Catenin
Substances
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CTNNB1 protein, human
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Cytoskeletal Proteins
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Proto-Oncogene Proteins
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Trans-Activators
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Wnt Proteins
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Zebrafish Proteins
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beta Catenin
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Protein-Tyrosine Kinases
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Calcium-Calmodulin-Dependent Protein Kinases
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Glycogen Synthase Kinase 3
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Phosphoprotein Phosphatases
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Protein Phosphatase 2