Abstract
The survival of multicellular organisms is dependent on their ability to recognize invading microbial pathogens and to induce a variety of defense reactions. Recent evidence suggests that an evolutionarily ancient family of Toll-like receptors plays a crucial role in the detection of microbial infection and the induction of immune and inflammatory responses.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Bacteria / metabolism*
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Drosophila / immunology
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Drosophila Proteins*
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Humans
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Immunity, Innate*
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Infections / immunology*
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Infections / microbiology
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Membrane Glycoproteins / metabolism*
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Mice
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Receptors, Cell Surface / metabolism*
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Signal Transduction
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Toll-Like Receptor 5
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Toll-Like Receptors
Substances
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Drosophila Proteins
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Membrane Glycoproteins
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Receptors, Cell Surface
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Toll-Like Receptor 5
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Toll-Like Receptors
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tehao protein, Drosophila