Abstract
A recent series of papers in Nature shows that low-density lipoprotein receptor-related protein family members play a role in transduction of Wnt signals. These findings, in addition to other work from the past two years, have important implications for the role of Wnts in neural development.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Cerebral Cortex / growth & development
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Cerebral Cortex / metabolism*
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Drosophila / genetics
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Humans
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Mutation / physiology
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Proto-Oncogene Proteins / physiology*
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Receptors, LDL / metabolism
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Receptors, LDL / physiology*
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Signal Transduction / physiology*
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Wnt Proteins
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Zebrafish Proteins*
Substances
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Proto-Oncogene Proteins
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Receptors, LDL
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Wnt Proteins
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Zebrafish Proteins