Abstract
Recent findings from the perirhinal cortex have shed new light on the ways in which metabotropic glutamate receptors could be involved in synaptic plasticity, and in particular in long-term depression (LTD) of synaptic transmission. Importantly, these findings have also led to a greater understanding of mechanisms that could regulate mglu-receptor signalling and the ways in which mglu receptors interact with one another.
MeSH terms
-
Animals
-
Calcium Signaling / drug effects
-
Calcium Signaling / physiology
-
Cyclic AMP / metabolism
-
Humans
-
Membrane Potentials / drug effects
-
Membrane Potentials / physiology
-
Neural Inhibition / drug effects
-
Neural Inhibition / physiology*
-
Parahippocampal Gyrus / metabolism*
-
Parahippocampal Gyrus / ultrastructure
-
Presynaptic Terminals / drug effects
-
Presynaptic Terminals / metabolism*
-
Presynaptic Terminals / ultrastructure
-
Receptors, Metabotropic Glutamate / drug effects
-
Receptors, Metabotropic Glutamate / metabolism*
-
Receptors, Metabotropic Glutamate / ultrastructure
-
Receptors, N-Methyl-D-Aspartate / drug effects
-
Receptors, N-Methyl-D-Aspartate / metabolism
-
Synaptic Membranes / drug effects
-
Synaptic Membranes / metabolism*
-
Synaptic Membranes / ultrastructure
-
Synaptic Transmission / drug effects
-
Synaptic Transmission / physiology*
Substances
-
Receptors, Metabotropic Glutamate
-
Receptors, N-Methyl-D-Aspartate
-
Cyclic AMP