New roles for ubiquitin in the assembly and function of neuronal circuits

Neuron. 2002 Sep 26;36(1):5-8. doi: 10.1016/s0896-6273(02)00943-1.

Abstract

A series of recent papers highlight a prominent role for ubiquitin in the formation and function of neural circuits. These new results focus attention on the molecular remodeling that occurs at various decision points in the life of growth cones and synapses.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Communication / physiology
  • Cell Differentiation / physiology*
  • Cell Membrane / metabolism
  • Central Nervous System / cytology
  • Central Nervous System / embryology*
  • Central Nervous System / metabolism
  • Chemotaxis / physiology
  • Growth Cones / metabolism*
  • Growth Cones / ultrastructure
  • Humans
  • Neural Pathways / cytology
  • Neural Pathways / embryology*
  • Neural Pathways / metabolism
  • Synapses / metabolism
  • Synapses / ultrastructure
  • Ubiquitin / metabolism*

Substances

  • Ubiquitin