The role of interleukin-6 in nociception and pain

Anesth Analg. 2003 Apr;96(4):1096-1103. doi: 10.1213/01.ANE.0000055362.56604.78.

Abstract

That IL-6 is an interesting target in the study of pain is underscored by its biomolecular properties, its localization after experimental pain, and its modulating effect on pain after administration.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Inflammation / metabolism
  • Inflammation / physiopathology
  • Inflammation Mediators / metabolism
  • Inflammation Mediators / physiology*
  • Interleukin-6 / metabolism
  • Interleukin-6 / physiology*
  • Neurons / drug effects
  • Nociceptors / drug effects
  • Nociceptors / physiology*
  • Pain / metabolism
  • Pain / physiopathology*

Substances

  • Inflammation Mediators
  • Interleukin-6