The ancestry of segmentation

Dev Cell. 2003 Jul;5(1):2-4. doi: 10.1016/s1534-5807(03)00197-7.

Abstract

Recent studies of segmentation in the spider suggest that the ancestral vertebrate and arthropod segmentation mechanisms utilized the Notch signaling pathway and bolster the argument that segmentation is an ancestral feature of all bilaterians.

MeSH terms

  • Animals
  • Body Patterning / genetics*
  • Body Patterning / physiology
  • Drosophila Proteins / genetics
  • Drosophila Proteins / metabolism
  • Drosophila melanogaster / embryology
  • Drosophila melanogaster / genetics
  • Evolution, Molecular
  • Gene Expression Regulation, Developmental
  • Insect Proteins / metabolism
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism
  • Mesoderm / metabolism
  • Phylogeny
  • Receptors, Notch
  • Signal Transduction
  • Somites / cytology
  • Somites / metabolism*
  • Spiders / embryology
  • Spiders / genetics
  • Vertebrates / genetics
  • Vertebrates / metabolism

Substances

  • Drosophila Proteins
  • Insect Proteins
  • Membrane Proteins
  • N protein, Drosophila
  • Receptors, Notch