Full-spectrum cone sensitivity functions for X-chromosome-linked anomalous trichromats

J Opt Soc Am A. 1992 Sep;9(9):1465-76. doi: 10.1364/josaa.9.001465.

Abstract

We derived the cone fundamentals for X-chromosome-linked anomalous trichromats for the wavelength range of 400-700 nm. Pigment templates were constructed from the cone fundamentals of normal trichromats after correction for ocular media absorption. The resultant retinal-level sensitivities had small irregularities in the short-wavelength region that were smoothed. The pigment templates, expressed as quantal sensitivities, were then shifted on a frequency abscissa to solve for the lambda max of the pigments of anomalous trichromats needed to predict average anomaloscope matching data. We found that the protanomalous M- and L'-cone pigments are separated by 10 nm and the deuteranomalous M'- and L-cone pigments are separated by 6 nm (rounded to the nearest nanometer), where M and L indicate middle- and long-wavelength sensitive, respectively. The triads of peak wavelengths for the corneal energy-based sensitivities were as follows: normal: 440, 543, and 566 nm; protanomalous: 440, 543, and 553 nm; and deuteranomalous: 440, 560, and 566 nm.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Color Vision Defects / genetics*
  • Color Vision Defects / physiopathology
  • Genetic Linkage*
  • Humans
  • Light
  • Male
  • Photoreceptor Cells / physiopathology*
  • Psychophysics
  • Retinal Pigments / chemistry*
  • Sensory Thresholds
  • X Chromosome*

Substances

  • Retinal Pigments