Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease

N Engl J Med. 1990 May 3;322(18):1293-8. doi: 10.1056/NEJM199005033221807.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aspartic Acid / analogs & derivatives*
  • Aspartic Acid / metabolism
  • Corpus Striatum / analysis
  • Corpus Striatum / pathology*
  • Female
  • Heterozygote
  • Humans
  • Huntington Disease / genetics
  • Huntington Disease / metabolism
  • Huntington Disease / pathology*
  • Immunohistochemistry
  • N-Methylaspartate
  • Neurons / pathology
  • Receptors, N-Methyl-D-Aspartate
  • Receptors, Neurotransmitter / analysis*
  • Substance P / analysis
  • Suicide

Substances

  • Receptors, N-Methyl-D-Aspartate
  • Receptors, Neurotransmitter
  • Aspartic Acid
  • Substance P
  • N-Methylaspartate