Abstract
A fundamental task of the brain is detecting patterns in the environment that enable predictions about the future. Here, we show that the salamander and mouse retinas can recognize a wide class of periodic temporal patterns, such that a subset of ganglion cells fire strongly and specifically in response to a violation of the periodicity. This sophisticated retinal processing may provide a substrate for hierarchical pattern detection in subsequent circuits.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Action Potentials / physiology
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Action Potentials / radiation effects
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Animals
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Dose-Response Relationship, Radiation
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In Vitro Techniques
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Larva
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Mice
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Mice, Inbred C57BL
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Periodicity*
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Photic Stimulation / methods
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Retina / cytology
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Retina / physiology*
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Retinal Ganglion Cells / physiology
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Retinal Ganglion Cells / radiation effects
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Time Factors
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Urodela
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Visual Fields / physiology*
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Visual Pathways / physiology*