Sleep and EEG spectra in rats recorded via telemetry during surgical recovery

Sleep. 2007 Aug;30(8):1057-61. doi: 10.1093/sleep/30.8.1057.

Abstract

Study objective: To determine sleep and EEG spectra in rats during surgical recovery.

Design: Sleep, activity, and EEG spectral power were examined in rats via telemetry on days 1, 2, 3, 7, 14, and 15 after implantation surgery.

Results: NREM sleep and total sleep were increased on days 1 and 2 compared to later days. REM sleep was decreased on days 2 and 3 compared to days 14 and 15, and activity was decreased on days 1 and 2 compared to later days. EEG power (0.5-5 Hz for NREM and wakefulness, and 5.5-10 Hz for REM and wakefulness) was increased on days 1-3 compared to days 7, 14, and 15.

Conclusion: The results are discussed in terms of their implications for post-surgery stabilization of sleep and potential relevance for sleep after injury.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anesthesia Recovery Period*
  • Animals
  • Cerebral Cortex / physiopathology*
  • Circadian Rhythm / physiology
  • Electrodes, Implanted*
  • Electroencephalography*
  • Fourier Analysis
  • Male
  • Motor Activity / physiology
  • Polysomnography*
  • Postoperative Period
  • Rats
  • Rats, Wistar
  • Signal Processing, Computer-Assisted*
  • Sleep Stages / physiology*
  • Theta Rhythm
  • Wakefulness / physiology