Abstract
A rat brain cDNA (Raw3) related to the Drosophila Shaw K+ channel family has been characterized. Raw3 cRNA leads to the formation of TEA-insensitive, fast inactivating (A-type) K+ channels when injected into Xenopus laevis oocytes. Raw3 channels have markedly different properties from the previously cloned rat A-type K+ channel RCK4, Raw3 channels operate in the positive voltage range.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Cloning, Molecular
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DNA / genetics
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Electric Conductivity
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Membrane Glycoproteins / genetics
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Molecular Sequence Data
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Oocytes
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Potassium Channels / drug effects
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Potassium Channels / genetics*
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Potassium Channels / physiology
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Rats
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Recombinant Proteins / physiology
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Xenopus laevis
Substances
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Membrane Glycoproteins
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Potassium Channels
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Recombinant Proteins
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DNA
Associated data
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GENBANK/X58797
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GENBANK/X58798
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GENBANK/X58799
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GENBANK/X58800
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GENBANK/X58801
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GENBANK/X58802
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GENBANK/X58803
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GENBANK/X62839
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GENBANK/X62840
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GENBANK/X62841