Abstract
Rewarding and aversive stimuli evoke very different patterns of behavior and are rapidly discriminated. Here taste stimuli of opposite hedonic valence evoked opposite patterns of dopamine and metabolic activity within milliseconds in the nucleus accumbens. This rapid encoding may serve to guide ongoing behavioral responses and promote plastic changes in underlying circuitry.
Publication types
-
Research Support, N.I.H., Extramural
MeSH terms
-
Analysis of Variance
-
Animals
-
Appetite / physiology
-
Avoidance Learning / physiology*
-
Behavior, Animal
-
Discrimination, Psychological / physiology*
-
Dopamine / metabolism*
-
Electric Stimulation / methods
-
Electrochemical Techniques / methods
-
Food Preferences / physiology
-
Hydrogen-Ion Concentration
-
Male
-
Motor Activity / physiology
-
Nucleus Accumbens / physiology*
-
Principal Component Analysis
-
Quinine / administration & dosage
-
Rats
-
Rats, Sprague-Dawley
-
Reward*
-
Sucrose / administration & dosage
-
Sweetening Agents / administration & dosage
-
Taste / physiology
-
Time Factors
Substances
-
Sweetening Agents
-
Sucrose
-
Quinine
-
Dopamine