Abstract
Using diffusion tensor imaging and tractography, we found that a disruption in structural connectivity in ventral occipito-temporal cortex may be the neurobiological basis for the lifelong impairment in face recognition that is experienced by individuals who suffer from congenital prosopagnosia. Our findings suggest that white-matter fibers in ventral occipito-temporal cortex support the integrated function of a distributed cortical network that subserves normal face processing.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Diffusion Magnetic Resonance Imaging
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Humans
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Middle Aged
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Occipital Lobe / pathology
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Occipital Lobe / physiopathology
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Prosopagnosia / congenital*
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Prosopagnosia / diagnosis
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Prosopagnosia / physiopathology*
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Temporal Lobe / pathology
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Temporal Lobe / physiopathology
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Visual Cortex / pathology
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Visual Cortex / physiopathology*
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Visual Pathways / pathology
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Visual Pathways / physiopathology*