Abstract
The immunohistochemical localization of manganese (Mn)-superoxide dismutase (Mn-SOD) was studied in the rat basal forebrain using polyclonal antibodies to Mn-SOD. Neurons of the basal forebrain exhibit a high density of Mn-SOD immunoreactivity. Double immunostaining with a monoclonal antibody to choline acetyltransferase demonstrated that both cholinergic and non-cholinergic neurons in the basal forebrain are intensely immunoreactive for Mn-SOD.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Choline O-Acetyltransferase / immunology
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Electrophoresis, Polyacrylamide Gel
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Fluorescent Antibody Technique
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Immunoblotting
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Immunohistochemistry
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Male
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Neurons / enzymology*
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Neurons / immunology
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Parasympathetic Nervous System / enzymology*
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Parasympathetic Nervous System / ultrastructure
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Rats
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Rats, Inbred Strains
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Superoxide Dismutase / immunology*
Substances
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Superoxide Dismutase
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Choline O-Acetyltransferase