The brain activity map project and the challenge of functional connectomics

A Paul Alivisatos; Miyoung Chun; George M Church; Ralph J Greenspan; Michael L Roukes; Rafael Yuste

doi:10.1016/j.neuron.2012.06.006

The brain activity map project and the challenge of functional connectomics

Neuron. 2012 Jun 21;74(6):970-4. doi: 10.1016/j.neuron.2012.06.006.

Authors

A Paul Alivisatos¹, Miyoung Chun, George M Church, Ralph J Greenspan, Michael L Roukes, Rafael Yuste

Affiliation

¹ Materials Science Division, Lawrence Berkeley National Lab and Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.

Abstract

The function of neural circuits is an emergent property that arises from the coordinated activity of large numbers of neurons. To capture this, we propose launching a large-scale, international public effort, the Brain Activity Map Project, aimed at reconstructing the full record of neural activity across complete neural circuits. This technological challenge could prove to be an invaluable step toward understanding fundamental and pathological brain processes.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Action Potentials / physiology
Brain / physiology*
Brain Mapping / methods*
Humans
Models, Neurological
Nerve Net / physiology*
Neural Pathways / physiology
Neurons / physiology

Abstract

Publication types

MeSH terms

Grants and funding