Behavioral plasticity, learning, and memory in C. elegans

Hiroyuki Sasakura; Ikue Mori

doi:10.1016/j.conb.2012.09.005

Behavioral plasticity, learning, and memory in C. elegans

Curr Opin Neurobiol. 2013 Feb;23(1):92-9. doi: 10.1016/j.conb.2012.09.005. Epub 2012 Oct 11.

Authors

Hiroyuki Sasakura¹, Ikue Mori

Affiliation

¹ Laboratory of Molecular Neurobiology, Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.

PMID: 23063296
DOI: 10.1016/j.conb.2012.09.005

Abstract

Caenorhabditis elegans exhibits behavior plasticity that appears to correspond to non-associative and associative learning, and short-term and long-term memory. Recent finding revealed that evolutionally conserved molecules such as insulin, monoamines, and neuropeptides are required for the plasticity. We propose the concept of human brain operation from the C. elegans studies.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Brain / physiology*
Caenorhabditis elegans / physiology*
Humans
Learning / physiology*
Memory / physiology*
Neuronal Plasticity / physiology*