Cytoskeleton: axons earn their stripes

Curr Biol. 2013 Mar 4;23(5):R197-8. doi: 10.1016/j.cub.2013.01.050.

Abstract

Axons must be supported by a strong and flexible cytoskeleton. New 'super-resolution' imaging of the submembranous axonal cytoskeleton reveals that it is organized in a periodic, ladder-like structure with alternating rings of actin linked together by intervening complexes of spectrin.

Publication types

  • Comment

MeSH terms

  • Actins / ultrastructure*
  • Animals
  • Axons / chemistry*
  • Axons / ultrastructure*
  • Calmodulin-Binding Proteins / ultrastructure*
  • Cytoskeleton / chemistry*
  • Cytoskeleton / ultrastructure*
  • Spectrin / ultrastructure*

Substances

  • Actins
  • Calmodulin-Binding Proteins
  • Spectrin