Recovery of the basilar papilla following intense sound exposure in the chick

Hear Res. 1990 Jul;46(3):229-37. doi: 10.1016/0378-5955(90)90004-9.

Abstract

Newly hatched chicks were exposed to a 900-Hz tone at 120 dB SPL for 48 hours, then sacrificed, along with unexposed controls, at intervals of 0-15 days following exposure. Examination of the basilar papilla by scanning electron microscopy demonstrated a 32% loss of hair cells within the lesion area with substantial shrinkage of the apical surfaces of the survivors. Within days, the papilla returned to a nearly normal appearance, and new hair cells were seen, but the number of new cells was only a fraction--approximately 22%--of the number lost. Expansion of the apical surfaces of the surviving cells to larger than normal size was a major factor in the recovery of the papilla.

MeSH terms

  • Animals
  • Basilar Membrane / pathology*
  • Basilar Membrane / physiology
  • Chickens
  • Cochlea / pathology*
  • Hair Cells, Auditory / pathology
  • Hair Cells, Auditory / physiology
  • Hearing Loss, Noise-Induced / pathology*
  • Hearing Loss, Noise-Induced / physiopathology
  • Microscopy, Electron, Scanning
  • Regeneration
  • Time Factors