CA3 sees the big picture while dentate gyrus splits hairs

Ehren L Newman; Michael E Hasselmo

doi:10.1016/j.neuron.2014.01.004

CA3 sees the big picture while dentate gyrus splits hairs

Neuron. 2014 Jan 22;81(2):226-8. doi: 10.1016/j.neuron.2014.01.004.

Authors

Ehren L Newman¹, Michael E Hasselmo²

Affiliations

¹ Center for Memory and Brain, Department of Psychology, Boston University, 2 Cummington Mall, Boston, MA 02215, USA. Electronic address: enewman@gmail.com.
² Center for Memory and Brain, Department of Psychology, Boston University, 2 Cummington Mall, Boston, MA 02215, USA.

PMID: 24462091
DOI: 10.1016/j.neuron.2014.01.004

Abstract

The dentate gyrus (DG) and area CA3 of the hippocampus have been long hypothesized to perform pattern separation and pattern completion, respectively. A new study published in this issue of Neuron, Neunuebel and Knierim (2014), provides strong empirical support for this functional dissociation.

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MeSH terms

Animals
Association Learning / physiology*
CA3 Region, Hippocampal / physiology*
Dentate Gyrus / physiology*
Male
Mental Recall / physiology*
Nerve Net / physiology*