A non-uniform equivalent cable model of membrane voltage changes in a passive dendritic tree

J Theor Biol. 1989 Nov 21;141(2):159-79. doi: 10.1016/s0022-5193(89)80015-3.

Abstract

A non-uniform equivalent cable model of membrane voltage changes in a passive dendritic tree extending Rall's equivalent cylinder model is presented. It is obtained from a combination of cable theory with the continuum approach. Replacing the fine structure of the branching dendrites by an equivalent, conductive medium characterized by averaged electrical parameters, the one-dimensional cable equations with spatially varying parameters are derived. While these equations can be solved in general only numerically, we were able to formulate a general branching condition (comprising Rall's 3/2 power relationship as a special case) under which analytical solutions can be deduced from those of the equivalent cylinder model. This model allows dendritic trees with a greater variety of branching patterns than before to be analytically treated.

MeSH terms

  • Animals
  • Cell Membrane / physiology*
  • Dendrites / physiology*
  • Mathematics
  • Membrane Potentials*
  • Models, Neurological