An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat

Brain Res. 1985 Apr 1;331(1):172-5. doi: 10.1016/0006-8993(85)90730-9.

Abstract

The origins of neuropeptide Y-like immunoreactive (NPYI) fibers in the paraventricular and dorsomedial hypothalamic nuclei of the rat were examined using immunohistochemistry. Destruction of the arcuate nucleus resulted in a marked decrease of NPYI fibers ipsilaterally in these nuclei, suggesting that most of NPYI fibers in these nuclei originate from NPYI neurons in the arcuate nucleus. These NPYI systems did not contain noradrenalin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arcuate Nucleus of Hypothalamus / metabolism
  • Dorsomedial Hypothalamic Nucleus / metabolism
  • Fluorescent Antibody Technique
  • Hypothalamus / metabolism*
  • Nerve Tissue Proteins / metabolism*
  • Neural Pathways / metabolism
  • Neuropeptide Y
  • Norepinephrine / metabolism
  • Paraventricular Hypothalamic Nucleus / metabolism
  • Rats
  • Tyrosine 3-Monooxygenase / metabolism

Substances

  • Nerve Tissue Proteins
  • Neuropeptide Y
  • Tyrosine 3-Monooxygenase
  • Norepinephrine