The aging brain

Clin Geriatr Med. 1985 Feb;1(1):61-94.

Abstract

Changes in neurons, glial cells, synapse morphologic and electrophysiologic appearance, and neurotransmission mechanisms during normal aging are considered for review in this article. These processes not only are fundamental in the neurobiology of normal aging but also are implicated in the pathogenesis of aging.

Publication types

  • Review

MeSH terms

  • Aging*
  • Alzheimer Disease / metabolism
  • Animals
  • Brain / cytology
  • Brain / physiology*
  • Brain Chemistry
  • Cell Nucleus
  • Dendrites
  • Humans
  • Lipofuscin / analysis
  • Memory
  • Neuroglia / cytology
  • Neurons / analysis
  • Neurons / cytology
  • Parasympathetic Nervous System / physiology
  • Sleep Wake Disorders / etiology
  • Sympathetic Nervous System / physiology
  • Synapses
  • Synaptic Transmission

Substances

  • Lipofuscin